Guide
BPC-157: A Research Peptide Overview
BPC-157 is a synthetic pentadecapeptide used as a model peptide in cell-based laboratory assays. This overview covers what it is, the pathways researchers study in vitro, how it is handled as a reference material, and why batch-level purity matters. It is written for laboratory research context only and makes no human-use claims.
What BPC-157 is
BPC-157 is a synthetic peptide of fifteen amino acids (sequence GEPPPGKPADDAGLV) corresponding to a partial sequence identified in gastric proteins. It carries CAS number 137525-51-0, the molecular formula C62H98N16O22, and a molecular weight of 1419.53 g/mol.
As a research reference material it is supplied as a lyophilized powder and characterised by HPLC for purity and mass spectrometry for identity.
Why it is studied
In laboratory research BPC-157 is used as a model peptide in cell-based assays of angiogenesis and endothelial cell migration — how cultured cells move and organise into vascular structures.
It also appears in gastrointestinal mucosal and tissue-pathway research models, in in vitro work on growth-factor and nitric-oxide signaling, and in peptide-stability and analytical-method development. No medical, therapeutic, or diagnostic claims are made.
Handling and storage
Optimal storage is at -20°C (-4°F), protected from moisture and light. Lyophilized peptides are kept dry and sealed, with original labeling retained so the batch number stays traceable for re-verification.
This overview does not cover preparation or use of any kind. That falls outside laboratory research reference use, and we do not provide that guidance.
Why purity and identity matter
A fifteen-residue peptide can be synthesised with a deletion or a substitution that leaves the bulk material looking clean on a chromatogram while the sequence itself is subtly wrong. Purity by HPLC and identity by mass spectrometry answer two different questions, and a serious report carries both.
This is why a per-batch Certificate of Analysis — one tied to the exact lot you receive — is more useful than a generic brand-level document.
How to verify a BPC-157 batch
Before relying on any batch, confirm three things: purity (an HPLC percentage), identity (a mass-spectrometry confirmation), and a traceable lot number with a test date. If the supplier lets you look up that batch’s report, you can match the documentation to the vial in hand.
See our guide on how to read a peptide COA for a field-by-field walkthrough.